A Novel Approach: Proteoglycan Mimics in Bone Tissue Engineering
When we think of bones, we often imagine them as rigid structures that support our bodies, protect vital organs, and enable movement.
Proteoglycan Errors in Embryonic Bone Development: A Closer Look
The critical role of proteoglycans in embryonic bone development is highlighted when genetic mutations are linked to skeletal disorders.
Proteoglycans and Growth Factors: Regulation of Bone Development
Proteoglycans (PGs) are massive supramolecular complexes, often exceeding 200 megadaltons (MDa) in size, and play a critical role in the bone extracellular matrix.
The Blueprint for Bones: Building with Proteoglycans
Proteoglycans are essential components of the extracellular matrix with roles in bone development including endochondral ossification, collagen fibrillogenesis, and mineral deposition.
Proteoglycans in Embryonic Bone Development: The Unsung Heroes
Molecular Matrix, Inc. has developed Osteo-P® BGS, a hyper-crosslinked polysaccharide bone graft substitute that mimics proteoglycans and is osteoconductive for bone repair.
Prolotherapy and the Use of Sugars in Orthopedics
Prolotherapy has been a part of modern orthopedic practices since the 1940s. It is growing in popularity not just in the U.S.